abstract：:Systemic Sclerosis (SSc) is an autoimmune disease characterized by fibrosis and vasculopathy. A key feature is the presence of T cells in inflammatory lesions. To establish the differences in peripheral blood T helper (Th) subpopulations in diffuse cutaneous (dc) and limited cutaneous (lc) SSc patients, blood samples ...

journal_title：Rheumatology international

authors： Rodríguez-Reyna TS,Furuzawa-Carballeda J,Cabiedes J,Fajardo-Hermosillo LD,Martínez-Reyes C,Díaz-Zamudio M,Llorente L

更新日期：2012-09-01 00:00:00

abstract：:The aim of this study is to observe the effect of different treatment time of millimeter wave (MMW) on chondrocyte apoptosis, caspase-3, caspase-8, and matrix metalloproteinase-13 (MMP-13) in rabbit knee osteoarthritis induced by anterior cruciate ligament transection (ACLT). Thirty-two New Zealand White rabbits were ...

journal_title：Rheumatology international

authors： Xia L,Luo QL,Lin HD,Zhang JL,Guo H,He CQ

更新日期：2012-09-01 00:00:00

abstract：:Acromegaly is a chronic endocrinopathy characterized by hypersecretion of growth hormone (GH) and consequently of insulin-like growth factor-1 (IGF-1). The arthropathy in acromegaly is the most frequent and important cause of morbidity and functional disability in acromegaly. Rheumatoid arthritis (RA) is a rarely repo...

journal_title：Rheumatology international

authors： Aydın Y,Coşkun H,Kır S,Yazici S,Kudaş Ö,Güngör A

更新日期：2012-09-01 00:00:00

abstract：:Solid organ transplantation is an important lifesaving procedure mainly performed in patients with end-stage organ failure such as liver cirrhosis, congestive heart failure, and end-stage renal disease. While these complications are among the most preventable adverse effects of solid organ transplantation, these are g...

journal_title：Rheumatology international

authors： Movassaghi S,Nasiri Toosi M,Bakhshandeh A,Niksolat F,Khazaeipour Z,Tajik A

更新日期：2012-08-01 00:00:00

abstract：:Adult-onset Still's disease (AOSD) is known as a systemic inflammatory disease of unknown etiology and pathogenesis, characterized by fever, skin eruptions, systemic organ involvement, and arthralgias. AOSD is difficult to diagnose because of its heterogeneous clinical manifestations and prevalence (although more prev...

journal_title：Rheumatology international

authors： de Graaff LC,ten Broek MR,Schweitzer DH

更新日期：2012-08-01 00:00:00

abstract：:Abnormal manifestations of central nervous system in system lupus erythematosus (SLE) patients are mainly caused by primary neuropsychiatric SLE (NP-SLE). We reported a new onset SLE patient who had secondary neuropsychiatric manifestations caused by Epstein-Barr virus (EBV) encephalitis. Although EBV has an uncertain...

journal_title：Rheumatology international

authors： Hongbo C,Hongzhen M,Lingzhi H,Maosheng X,Mei C

更新日期：2012-08-01 00:00:00

abstract：:Systemic sclerosis (SSc) is a chronic autoimmune connective tissue disease. Of the numerous organ manifestations, involvement of the upper and lower gastrointestinal tract (GIT) appears to be the most frequent with regard to the clinical symptoms. However, as the frequency and clinical relevance of GI involvement in p...

journal_title：Rheumatology international

authors： Schmeiser T,Saar P,Jin D,Noethe M,Müller A,Soydan N,Hardt PD,Jaeger C,Distler O,Roeb E,Bretzel RG,Müller-Ladner U

更新日期：2012-08-01 00:00:00

abstract：:Sleep disturbances and problems are increased in ankylosing spondylitis (AS). But much is not known in a quantitative way about sleep problems and effect of treatments on AS. This study is aimed first, to investigate sleep disturbances in AS and secondly, to evaluate the effects of anti-TNF treatment on SD in AS. One ...

journal_title：Rheumatology international

authors： Karadağ O,Nakas D,Kalyoncu U,Akdoğan A,Kiraz S,Ertenli I

更新日期：2012-07-01 00:00:00

abstract：:To investigate the expression and effect of farnesoid X receptor (FXR) on systemic lupus erythematosus (SLE) liver dysfunction and indicate its hepatoprotective role and the immunomodulatory property. mRNA and protein levels of FXR were determined on the liver specimens of SLE patients with liver injury as well as MRL...

journal_title：Rheumatology international

authors： Lian F,Wang Y,Chen J,Xu H,Yang X,Liang L,Zhan Z,Ye Y,Chen M

更新日期：2012-06-01 00:00:00

abstract：:Malignant neoplasms are associated with a wide variety of paraneoplastic rheumatological syndromes. The paraneoplastic nature should be based on specific criteria. We report a series of eight cases of paraneoplastic rheumatic syndromes revealing an underlying neoplasia. Our series consists of six men and two women, wi...

journal_title：Rheumatology international

authors： Hakkou J,Rostom S,Bahiri R,Hajjaj-Hassouni N

更新日期：2012-06-01 00:00:00

abstract：:Wegener granulomatosis (WG) is a necrotizing granulomatous vasculitis that predominantly affects airways and kidneys. But central nervous system involvement (7-11%) is an uncommon. Massive ICH may occur in the course of WG, and this serious condition is related with high risk of mortality. Therefore, the new treatment...

journal_title：Rheumatology international

authors： Ceri M,Ortabozkoyun L,Unverdi S,Kirac M,Duranay M

更新日期：2012-06-01 00:00:00

abstract：:Reported here is a 19-year-old female patient with familial Mediterranean fever who was seen for altered mental status and seizures. She was eventually diagnosed to have posterior reversible leukoencephalopathy syndrome. Although a variety of conditions have been reported in association with this syndrome, to our best...

journal_title：Rheumatology international

authors： Ulaşlı AM,Kutlu G,Kocatürk Ö,Özçakar L

更新日期：2012-06-01 00:00:00

abstract：:A 41-year-old woman with SAPHO syndrome presented with numbness of her left arm followed by a generalized seizure. Computed tomography and magnetic resonance imaging of the brain revealed a small ring enhancing lesion in the right parietal lobe with adjacent meningeal thickening and enhancement. Surgical removal and h...

journal_title：Rheumatology international

authors： Abul-Kasim K,Nilsson T,Turesson C

更新日期：2012-06-01 00:00:00

abstract：:To investigate the efficacy of etanercept and MTX (methotrexate) combination therapy in Chinese patients with ankylosing spondylitis hip joint lesion, the possible courses and maintenance protocol, altogether 97 ankylosing spondylitis patients fulfilling the modified New York criteria with hip joint lesion were enroll...

journal_title：Rheumatology international

authors： Lian F,Yang X,Liang L,Xu H,Zhan Z,Qiu Q,Ye Y

更新日期：2012-06-01 00:00:00

abstract：:Isoform 4 of the human peptidylarginine deiminase (hPAD4) enzyme may be responsible for the citrullination of antigens in rheumatoid arthritis (RA) and has been shown to be itself the target of disease-specific autoantibodies. Here, we have tested whether the level of serum anti-hPAD4 antibodies in RA patients is stab...

journal_title：Rheumatology international

authors： Pollmann S,Stensland M,Halvorsen EH,Sollid LM,Kvien TK,Fleckenstein B,Molberg O

更新日期：2012-05-01 00:00:00

abstract：:Joint destruction and excessive bone formation are associated with high expression of soluble receptor activator of nuclear factor-κB ligand (sRANKL). This study was undertaken to investigate the role of sRANKL in collagenase-induced osteoarthritis (CIOA) in mice and in patients with osteoarthritis (OA). The initial p...

journal_title：Rheumatology international

authors： Dimitrova P,Toncheva A,Gyurkovska V,Ivanovska N

更新日期：2012-05-01 00:00:00

abstract：:The aim of the study was to test the frequency of CD4+ CD25(high)FoxP3 regulatory T cells in JIA patients and to assess their activation status and functional activity. The study involved 12 children with JIA and 35 healthy control subjects. PBMC were stained with monoclonal antibodies (anti-CD25, anti-CD4, anti-CD127...

journal_title：Rheumatology international

authors： Stelmaszczyk-Emmel A,Jackowska T,Rutkowska-Sak L,Marusak-Banacka M,Wąsik M

更新日期：2012-05-01 00:00:00

abstract：:Sarcoidosis is a chronic, multisystemic, non-caseating granulomatous disease of unknown etiology. Nasopharyngeal involvement is very rare in sarcoidosis. The objective of this report was to evaluate a rare involvement of sarcoidosis. This report includes a case of nasopharyngeal sarcoidosis. A 51-year-old female with ...

journal_title：Rheumatology international

authors： Akin S,Akin S,Karadag O,Kalyoncu U,Balcı S,Ozgen B

更新日期：2012-05-01 00:00:00

abstract：:Fibrodysplasia ossificans progressiva (FOP) is a rare but extremely disabling genetic disease of the skeletal system. This disease is characterized by progression of heterotopic ossification within skeletal muscles, ligaments and tendons. Most patients with FOP are misdiagnosed early in life before the appearance of h...

journal_title：Rheumatology international

authors： Ulusoy H

更新日期：2012-05-01 00:00:00

abstract：:Diffuse idiopathic skeletal hyperostosis (DISH) is difficult to distinguish from various forms of inflammatory arthritis, including psoriatic arthritis (PsA), rheumatoid arthritis, and ankylosing spondylitis. A 67-year-old Japanese male had been treated for psoriasis vulgaris for 13 years. Numbness of his right arm an...

journal_title：Rheumatology international

authors： Taniguchi T,Maejima H,Watarai A,Aki R,Katsuoka K

更新日期：2012-05-01 00:00:00

abstract：:Sjogren's syndrome (SS) is a systemic autoimmune disease characterized by xerophthalmia, xerostomia and extraglandular manifestations. Anemia, leukopenia, thrombocytopenia and lymphoproliferative disorders, including lymphoma are well-known extraglandular, hematological complications of SS. We report here a rare case ...

journal_title：Rheumatology international

authors： Choung BS,Yoo WH

更新日期：2012-05-01 00:00:00

abstract：:Pure red cell aplasia (PRCA) is a disease with important relationships to autoimmune mechanisms. Although some autoimmune diseases, such as rheumatoid arthritis and systemic lupus erythematosus, have been associated with PRCA, until this point no studies have described the association between PRCA and primary antiphos...

journal_title：Rheumatology international

authors： Caldas CA,de Carvalho JF

更新日期：2012-05-01 00:00:00

abstract：:Uveitis in juvenile idiopathic arthritis (JIA) is frequently associated with the development of complications and visual loss. Topical corticosteroids are the first-choice therapy, and immunosuppression is commonly used. However, treatment has not been standardized. Representatives from the German Ophthalmological Soc...

journal_title：Rheumatology international

authors： Heiligenhaus A,Michels H,Schumacher C,Kopp I,Neudorf U,Niehues T,Baus H,Becker M,Bertram B,Dannecker G,Deuter C,Foeldvari I,Frosch M,Ganser G,Gaubitz M,Gerdes G,Horneff G,Illhardt A,Mackensen F,Minden K,Pleyer U,

更新日期：2012-05-01 00:00:00

abstract：:Circulating endothelial progenitor cells (EPCs) are reduced in patients with systemic lupus erythematosus (SLE). A reduced number of EPCs are associated with the presence of atherosclerosis in other populations. We sought to determine whether the reduction in EPC numbers in SLE is dependent on the presence of advanced...

journal_title：Rheumatology international

authors： Baker JF,Zhang L,Imadojemu S,Sharpe A,Patil S,Moore JS,Mohler ER 3rd,Von Feldt J

更新日期：2012-04-01 00:00:00

abstract：:The aim of the study is to determine the prevalence of and factors associated with major depression among those with Fibromyalgia Syndrome (FMS) in a Canadian representative sample. The study was a secondary analysis of a large, nationally representative sample from the Canadian Community Health Survey. The full sampl...

journal_title：Rheumatology international

authors： Fuller-Thomson E,Nimigon-Young J,Brennenstuhl S

更新日期：2012-04-01 00:00:00

abstract：:Wells' syndrome is a multifaceted dermatosis with a wide morphological spectrum, ranging from characteristic cellulitis-like erythema and papula to an unusual presentation of vesicles and pustules. The most important elements for diagnosis are erythemal plaques and histological picture of eosinophilic infiltration of ...

journal_title：Rheumatology international

authors： Yin G,Xie Q

更新日期：2012-04-01 00:00:00

abstract：:Our study was aimed to clarify an association between gastrointestinal (GI) amyloid-positive area and various kinds of factors including renal function in reactive amyloidosis associated with rheumatoid arthritis (RA). Twenty-five patients with an established diagnosis of reactive AA amyloidosis participated in the st...

journal_title：Rheumatology international

authors： Kuroda T,Tanabe N,Kobayashi D,Sato H,Wada Y,Murakami S,Nakano M,Narita I

更新日期：2012-04-01 00:00:00

abstract：:The objective of this study was to report 11 cases of propylthiouracil (PTU)-induced autoimmune syndromes. We describe the clinical presentation, course, and outcome of 11 patients and compare clinical features between PTU-induced lupus and PTU-induced vasculitis. Of our 11 patients, 7 patients had vasculitis and 4 pa...

journal_title：Rheumatology international

authors： Wu R,Li R

更新日期：2012-03-01 00:00:00

abstract：:The minor allele of the non-synonymous single nucleotide polymorphism (SNP) +1858C>T within the PTPN22 gene has now been unequivocally confirmed as conferring susceptibility to RA in population from Europe and America, but not in population from Asia. The aim of this study was to jointly address and integrate these se...

journal_title：Rheumatology international

authors： Huang JJ,Qiu YR,Li HX,Sun DH,Yang J,Yang CL

更新日期：2012-03-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) is a chronic inflammatory disease that can lead to damage to several vital organs. Antiphospholipid syndrome (APS), manifesting as vascular thromboembolic events and morbidities of pregnancy in the presence of antiphospholipid antibodies (aPL), has been described in patients with SLE...

journal_title：Rheumatology international

authors： Lu CC,Chen CH,Yeh SF,Lai JH,Chang DM

更新日期：2012-03-01 00:00:00

abstract：:The objective of this study is to describe the interstitial lung disease (ILD) in rheumatoid arthritis (RA) patients of China, and to study clinical significance of high-resolution computed tomography (HRCT) in evaluation and treatment. One hundred and ten Chinese patients (79 women and 31 man) diagnosed with RA betwe...

journal_title：Rheumatology international

authors： Zou YQ,Li YS,Ding XN,Ying ZH

更新日期：2012-03-01 00:00:00

abstract：:A 7-year-old child was first admitted for persistent fever of 15-day duration and suspected meningitis. Kawasaki syndrome was lately diagnosed upon the recognition of an extensive diffuse coronary artery damage characterized by medium-sized aneurysms of the epicardial vessels. An eccentric thrombus along the inferior ...

journal_title：Rheumatology international

authors： De Rosa G,Cefalo MG,Marano R,Piastra M,Delogu AB,Rigante D

更新日期：2012-03-01 00:00:00

abstract：:Giant cell arteritis (GCA) is the most common systemic vasculitis affecting people over 50 years. This disease is a diagnostic challenge with a range of clinical symptoms and findings due to different affected vessels. Because of this, the initial diagnosis can be tricky, and some of the patients present at first time...

journal_title：Rheumatology international

authors： Husein-Elahmed H,Callejas-Rubio JL,Rios-Fernández R,Ortego-Centeno N

更新日期：2012-03-01 00:00:00

abstract：:We have investigated the role of the Th17-related cytokines interleukin-17A (IL-17A), IL-21, and IL-23 in spondyloarthritis (SpA) by examining their association with disease activity and magnetic resonance imaging (MRI) findings in patients with SpA (n = 80). Furthermore, to investigate the cellular origins of the cyt...

journal_title：Rheumatology international

authors： Andersen T,Rasmussen TK,Hvid M,Holm CK,Madsen KJ,Jurik AG,Hokland M,Stengaard-Pedersen K,Schiøttz-Christensen B,Deleuran B

更新日期：2012-02-01 00:00:00

abstract：:Recent studies indicate that high-mobility group box protein 1 (HMGB1) contributes to the pathogenesis of diverse autoimmune disorders. It induces the production of interferon-alpha (IFN-alpha) and tumor necrosis factor alpha (TNF-alpha) in vitro. In the present study, plasma HMGB1, TNF-alpha, and IFN-alpha were deter...

journal_title：Rheumatology international

authors： Ma CY,Jiao YL,Zhang J,Yang QR,Zhang ZF,Shen YJ,Chen ZJ,Zhao YR

更新日期：2012-02-01 00:00:00

abstract：:Diabetic muscular infarct (DMI) is a rare condition, which begins with acute onset of extremity pain and swelling. Patients usually have long-standing disease and poorly controlled diabetes mellitus (DM). Thigh muscle group is the most commonly involved side, while lower leg involvement is rare. We represent herein a ...

journal_title：Rheumatology international

authors： Uçan H,Alemdaroğlu E,Yoldaş TK,Erdem Özdamar S,Akyüz M,Hatipoğlu C

更新日期：2012-02-01 00:00:00

abstract：:The objective of the study was to determine whether cartilage expression of the bone regulating molecules receptor activator of nuclear factor κB ligand (RANKL) and osteoprotegerin (OPG) varies between the different grades of osteoarthritis (OA). Cartilage samples were obtained from 30 patients undergoing total hip/kn...

journal_title：Rheumatology international

authors： Upton AR,Holding CA,Dharmapatni AA,Haynes DR

更新日期：2012-02-01 00:00:00

abstract：:This study examines whether or not MBD4 polymorphism is a marker for rheumatoid arthritis (RA) susceptibility or severity for Chinese patients in Taiwan. This study included 193 patients with RA, while 190 unrelated healthy individuals living in Central Taiwan served as controls. The relationship between MBD4 polymorp...

journal_title：Rheumatology international

authors： Huang CM,Huang PH,Chen CL,Wan L,Tsai CH,Liu SC,Huang WL,Tsai FJ

更新日期：2012-01-01 00:00:00

abstract：:Genetic polymorphisms in cytokine genes, which influence gene expression, may have an important impact on SLE susceptibility and severity. The aim of this study was to examine the possible influence of two functional polymorphisms in cis-regulatory regions of IL12B gene in the susceptibility and clinical symptoms of S...

journal_title：Rheumatology international

authors： Miteva LD,Manolova IM,Ivanova MG,Rashkov RK,Stoilov RM,Gulubova MV,Stanilova SA

更新日期：2012-01-01 00:00:00

abstract：:Previous studies showed a link between systemic lupus erythematosus (SLE) and Epstein-Barr virus (EBV) infection. We sought to determine the features of serologic response to EBV in SLE patients and whether this response differs from those of systemic sclerosis (SSc) and primary antiphospholipid syndrome (PAPS) patien...

journal_title：Rheumatology international

authors： Esen BA,Yılmaz G,Uzun S,Ozdamar M,Aksözek A,Kamalı S,Türkoğlu S,Gül A,Ocal L,Aral O,Inanç M

更新日期：2012-01-01 00:00:00